The HTRA2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to HTRA2. This antibody recognizes Human antigen. The HTRA2 Antibody has been validated for the following applications: ELISA, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive